Part 9: Fluid Therapy in Surgical Disorders

43: Intraoperative Fluid Therapy

 

Chapter outlines

Intravascular Volume Disturbances
Causes of hypovolemia
Selecting Appropriate Type of Fluid
Crystalloids
- Balanced crystalloids
- Normal saline
Colloids
- Albumin
- Hydroxyethyl starch
- Gelatine
Blood products
Quantity and Strategy for Fluid Administration
Minimal or moderate trauma surgery
Major invasive surgery
- The traditional approach
- Restrictive versus liberal fluid therapy
- Goal-directed fluid therapy
Monitoring
Intraoperative hypovolemia and hypotension are common in high-risk prolonged surgeries, such as major abdominal or cardiac procedures, among vulnerable populations, including elderly patients and those with preexisting medical conditions, and are associated with high morbidity, risk of postoperative mortality, and adverse postoperative outcomes [1, 2].
Proper fluid therapy is an essential and critical component of intraoperative management. Its goal is to prevent and correct hypovolemia and hypotension while avoiding fluid overload. Fluid overload is harmful as it carries the risk of impaired tissue oxygenation, pulmonary edema, impaired wound healing, acute kidney injury (AKI), prolonged bowel dysfunction, and longer hospital stay in surgical patients [3, 4]. Adequate fluid therapy ensures proper tissue perfusion and oxygenation, which are crucial for maintaining optimal surgical outcomes.

CAUSES OF INTRAVASCULAR VOLUME DISTURBANCES

Hypovolemia: To avoid hypovolemia and hypotension, along with appropriate fluid replacement, it is essential to diagnose and treat the underlying causes. Causes of intraoperative hypovolemia and hypotension include [5, 6]:
  1. Surgical blood loss: This is a major cause of hypovolemia, and the volume of blood loss depends on several factors, including the type and duration of the surgery, as well as any preexisting or acquired defects in hemostasis. Trauma surgery is the most common cause of severe blood loss. Concurrently, the use of anticoagulant therapies like warfarin, and antiplatelet agents such as clopidogrel, can further elevate the risk of bleeding during surgery.

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